Sunday 13 January 2013

Biochemistry of Tyrosinemia [TYPE 3]

Good afternoon! :)
How was your weekend so far? Hope it has been great for you!
Now, we are going to learn about the biochemistry of Type III Tyrosinemia today!
Yes it's the last type! Woohoo~




The HPD enzyme, which is found in the kidneys and liver, is responsible for converting 4-hydroxyphenylpyruvate into homogentisate in the catabolic pathway of tyrosine. The deficiency of HPD enzyme will result in accumulation of 4-hydroxyphenylpyruvate and its metabolites in the organs.

This is  one of our last few posts because we are running out of knowledge to share with you guys regarding Tyrosinemia... :(
Do continue to check back daily though~ We still have a bit more to share!

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